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Tocris Bioscience™ PF CBP1

Selective CBP/p300 bromodomain inhibitor

Supplier:  Tocris Bioscience™ 5801/50

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Catalog No. 580150

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

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Description

Description

Selective CBP/p300 bromodomain inhibitor (IC50 values are 125 and 363 nM, respectively). Exhibits >100-fold selectivity for CBP over BRD4. Also exhibits selectivity over a panel of other bromodomains. Reduces LPS-induced IL-1β, IL-6 and IFN-β expression in macrophages in vitro. Also downregulates RGS4 expression in primary cortical neurons in vitro.

Negative Control also available.

Specifications

Specifications

5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
50 mg
C29H36N4O3
>98%
1962928-21-7
Bromodomain Inhibitors
488.62
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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