PF4 Monoclonal Antibody (RTO), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA517639

Catalog No. PIMA517639

Description

MA5-17639 targets Platelet Factor 4 in ELISA and WB applications and shows reactivity with Human samples. The MA5-17639 immunogen is human Factor IV purified from the supernatant of thrombin activated platelets.

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).

Specifications

• Antigen: PF4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P02776
• Gene Symbols: Pf4
• Immunogen: Human Factor IV purified from the supernatant of thrombin activated platelets.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot
• Clone: RTO
• Conjugate: Unconjugated
• Gene: Pf4
• Gene Alias: chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; Cxcl4; Endothelial cell growth inhibitor; Iroplact; oncostatin-A; PF4; PF-4; Pf4a; Platelet factor 4; Platelet factor 4, short form; RATPF4A; Scyb4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5196
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid