Invitrogen™ PF4V1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521944

Catalog No. PIPA521944

Description

Recommended positive controls: A431, H1299, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PF4V1 (Platelet Factor 4 Variant 1) gene, located on chromosome 4q12, encodes a protein that is a member of the CXC chemokine family, sharing significant homology with platelet factor 4 (PF4/CXCL4). PF4V1 is primarily expressed in megakaryocytes and platelets, playing a role in modulating coagulation and inflammatory responses. The protein has chemotactic activity, attracting immune cells to sites of injury or inflammation. Furthermore, PF4V1 can bind to heparin, influencing the anticoagulant activity of heparin and potentially impacting hemostasis and thrombosis. Research suggests that variations in the expression or function of PF4V1 might contribute to different pathological conditions, including cardiovascular disease and inflammatory disorders.

Specifications

• Antigen: PF4V1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PF4V1
• Gene Alias: C-X-C motif chemokine 4; C-X-C motif chemokine 4 variant; CXCL4L1; CXCL4V1; PF4A; PF4alt; PF4-ALT; PF4V1; PF4var1; platelet factor 4 variant; platelet factor 4 variant 1; Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74); platelet factor 4, variant 1 (PF4-like); SCYB4V1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5197
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P10720
• Gene Symbols: PF4V1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PF4V1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG