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Tocris Bioscience™ PFI 1
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Catalog No. 444550
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Catalog No. Quantity
44-455-0 50 mg
44-451-0 10 mg
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Catalog No. 44-455-0 Supplier Tocris Bioscience™ Supplier No. 4445/50
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Description

BET bromodomain inhibitor

Potent BET bromodomain inhibitor; exhibits inhibitory activity at bromodomain-containing protein (BRD) 2 and BRD4 (IC50 values are 98 and 220 nM respectively). Induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). Also downregulates Aurora B expression in MV4;11 cells. Cell permeable.

Chemical Identifiers

CAS 1403764-72-6
Molecular Formula C16H17N3O4S

Specifications

Quantity 50 mg
Formula Weight 347.39
Purity >98%
Molecular Weight (g/mol) 347.389
Chemical Name or Material PFI 1

Safety and Handling

Recommended Storage Store at Room Temperature
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