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Tocris Bioscience™ PFI 3

Potent and selective SMARCA2/4 and polybromo 1 inhibitor

Manufacturer:  Tocris Bioscience™ 5072/10

Catalog No. 50-721-0


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Description

Description

PFI 3 is a potent and selective polybromo 1 (PBRM1) and SMARCA4 inhibitor (Kd values are 48 and 89 nM respectively) that also inhibits SMARCA2. This compoud displays 30-fold selectivity over other sub-family branches. PFI 3 accelerates FRAP recovery in cells at a concentration of 1 μM.
Specifications

Specifications

(2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one
C19H19N3O2
10 mg
1819363-80-8
321.37
98%
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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