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Invitrogen™ PFTK1 Polyclonal Antibody
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Catalog No. PIPA553293
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100 μL
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PIPA553293 100 μL
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Catalog No. PIPA553293 Supplier Invitrogen™ Supplier No. PA553293
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DDTTFDEICV TKMSTRNCQG MDSVIKPLDT IPEDKKVRVQ RTQSTFDPFE KPANQVKRVH SENNACINFK TSSTGKESPK VRRHSSPSSP TSPKFGKADS YEKLEKLGEG SYATVYKGKS KVNG Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 23%.

CDK14 (PFTK1)/cyclin Y is a member of the CDC2-related protein kinase family which is expressed primarily in the postnatal and adult nervous system. CDK14 is expressed at high levels in brain, pancreas, kidney, heart, testis, and ovary. CDK14 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms, while ser120 may contribute slightly to CDK14 binding. CDK14 acts as a cyclin-dependent kinase that regulates cell cycle progression and cell proliferation. Overexpression of CDK14 predicts resistance to chemotherapy in patients with esophageal squamous cell carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PFTK1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cdk14
Gene Accession No. O94921
Gene Alias Cdk14; Cell division protein kinase 14; cyclin dependent kinase 14; cyclin-dependent kinase 14; hPFTAIRE1; Kiaa0834; mKIAA0834; PFTAIRE protein kinase 1; PFTAIRE1; Pftk1; Serine/threonine-protein kinase PFTAIRE-1
Gene Symbols Cdk14
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PFTK1. Recombinant protein control fragment (Product #RP-91420).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5218
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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