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PFTK2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA528595
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PIPA528595 100 μL
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Catalog No. PIPA528595 Supplier Thermo Scientific Supplier No. PA528595

Rabbit Polyclonal Antibody

Recommended positive controls: H1299, HepG2. Predicted reactivity: Mouse (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PFTK2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene CDK15
Gene Accession No. Q96Q40
Gene Alias ALS2CR7; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 7; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein homolog; Cdk15; Cell division protein kinase 15; cyclin dependent kinase 15; cyclin-dependent kinase 15; frizzled family receptor 7; Fzd7; PFTAIRE protein kinase 2; PFTAIRE2; PFTK2; serine/threonine protein kinase; serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2
Gene Symbols CDK15
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 14 and 419 of Human PFTK2
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65061
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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