PGA3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549728
The antibody detects endogenous level of total PGA3 protein.Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Pepsin A is a member of the subfamily A1 within the pepsin family and is the predomit endopeptidase in the gastric juice of vertebrates. Pepsin A is inhibited by ovUS-1, a uterine serpin.
|Synthetic peptide corresponding to a region derived from 112-125 amino acids of Human pepsinogen 3, group I (pepsinogen A)|
|Antigen affinity chromatography|
|ELISA, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|Pepsinogen 3, group I (pepsinogen A), PGA4, PGA5|
|-20° C, Avoid Freeze/Thaw Cycles|
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