Invitrogen™ PGAM1 Monoclonal Antibody (GT256)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527770

Catalog No. PIMA527770

Description

Positive Control: 293T, A431, HeLa, HepG2, mouse brain, rat brain Predicted Reactivity: Xenopus laevis (84%), Chicken (92%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specifications

• Antigen: PGAM1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P18669, P25113, Q9DBJ1
• Gene Symbols: PGAM1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PGAM1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: GT256
• Conjugate: Unconjugated
• Gene: PGAM1
• Gene Alias: 2310050F24Rik; BPG-dependent PGAM 1; CDABP0006; epididymis secretory protein Li 35; HEL-S-35; PGAM1; Pgam-1; PGAMA; PGAM-B; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase isozyme B; RP11-452K12.8; similar to phosphoglycerate mutase
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 18648, 24642, 5223
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid