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Invitrogen™ PGAM1 Polyclonal Antibody
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Catalog No. PIPA522352
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100 μL
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PIPA522352 100 μL
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Catalog No. PIPA522352 Supplier Invitrogen™ Supplier No. PA522352
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain, 293T. Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Xenopus laevis (84%), Chicken (92%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGAM1
Applications Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene PGAM1
Gene Accession No. P18669, Q9DBJ1
Gene Alias 2310050F24Rik; BPG-dependent PGAM 1; CDABP0006; epididymis secretory protein Li 35; HEL-S-35; PGAM1; Pgam-1; PGAMA; PGAM-B; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase isozyme B; RP11-452K12.8; similar to phosphoglycerate mutase
Gene Symbols PGAM1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PGAM1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18648, 5223
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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