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Invitrogen™ PGAM1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA596268
Description
Immunogen sequence: MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL PSCESLKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL RGIVKHLEGL SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVR KAMEAVAAQG KAKK; Positive Samples: U-251MG, LO2, A375, MCF7, NIH/3T3, Mouse brain, Mouse kidney, Mouse liver, Rat spinal cord.
PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Specifications
PGAM1 | |
Polyclonal | |
Unconjugated | |
PGAM1 | |
2310050F24Rik; BPG-dependent PGAM 1; CDABP0006; epididymis secretory protein Li 35; HEL-S-35; PGAM1; Pgam-1; PGAMA; PGAM-B; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase isozyme B; RP11-452K12.8; similar to phosphoglycerate mutase | |
Rabbit | |
Affinity Chromatography | |
RUO | |
18648, 24642, 5223 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot, Immunocytochemistry | |
0.22 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P18669, P25113, Q9DBJ1 | |
PGAM1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human PGAM1 (NP_0026201). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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