Invitrogen™ PGAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596859

Catalog No. PIPA596859

Description

Immunogen sequence: MATHRLVMVR HGESTWNQEN RFCGWFDAEL SEKGTEEAKR GAKAIKDAKM EFDICYTSVL KRAIRTLWAI LDGTDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEE QVKIWRRSFD IPPPPMDEKH PYYNSISKER RYAGLKPGEL PTCESLKDTI ARALPFWNEE IVPQIKAGKR VLIAAHGNSL RGIVKHLEGM SDQAIMELNL PTGIPIVYEL NKELKPTKPM QFLGDEETVR KAMEAVAAQG KAK; Positive Samples: 22Rv1, SH-SY5Y, U-87MG, Mouse kidney, Mouse testis, Mouse skeletal muscle, Mouse brain, Rat kidney, Rat skeletal muscle.

Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X.

Specifications

• Antigen: PGAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pgam2
• Gene Alias: BPG-dependent PGAM 2; D14Mgh1; EGK_13739; GSD10; Muscle-specific phosphoglycerate mutase; Pgam2; PGAMM; PGAM-M; Pgmut; Phosphoglycerate mutase 2; phosphoglycerate mutase 2 (muscle); phosphoglycerate mutase isozyme M; phosphoglycerate mutase muscle-specific subunit
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24959, 5224, 56012
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.70 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O70250, P15259, P16290
• Gene Symbols: Pgam2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human PGAM2 (NP_0002812).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG