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Invitrogen™ PGAM5 Monoclonal Antibody (CL0624)
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Catalog No. PIMA524616
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100 μL
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Catalog No. Quantity
PIMA524616 100 μL
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Catalog No. PIMA524616 Supplier Invitrogen™ Supplier No. MA524616
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Description

Mouse Monoclonal Antibody

Immunogen sequence: NWDRREPLSL INVRKRNVES GEEELASKLD HYKAKATRHI FLIRHSQYHV DGSLEKDRTL TPLGREQAEL TGLRLASLGL KFNKIV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%. Binds to an epitope located within the peptide sequence NWDRREPLSLINVRK as determined by overlapping synthetic peptides.

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGAM5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL0624
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PGAM5
Gene Accession No. Q96HS1
Gene Alias 2610528A17Rik; Bcl-XL-binding protein v68; BXLBV68; PGAM family member 5, mitochondrial serine/threonine protein phosphatase; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; PGAM5; Phosphoglycerate mutase family member 5; RGD1312028; serine/threonine-protein phosphatase PGAM5, mitochondrial
Gene Symbols PGAM5
Host Species Mouse
Immunogen Recombinant protein fragment of Human PGAM5 (Product #RP-95712).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192111
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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