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PGAM5 Mouse anti-Human, Clone: CL0624, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524616

Catalog No. PIMA524616


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Description

Description

Immunogen sequence: NWDRREPLSL INVRKRNVES GEEELASKLD HYKAKATRHI FLIRHSQYHV DGSLEKDRTL TPLGREQAEL TGLRLASLGL KFNKIV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%. Binds to an epitope located within the peptide sequence NWDRREPLSLINVRK as determined by overlapping synthetic peptides.

This protein displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and may be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
Specifications

Specifications

PGAM5
Monoclonal
0.7 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q96HS1
BXLBV68, phosphoglycerate mutase family member 5
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
192111
Immunohistochemistry, Western Blot
CL0624
Unconjugated
PGAM5
Liquid
PGAM5
Recombit protein corresponding to Human PGAM5
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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