Invitrogen™ PGAM5 Monoclonal Antibody (CL0624)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524616

Catalog No. PIMA524616

Description

Immunogen sequence: NWDRREPLSL INVRKRNVES GEEELASKLD HYKAKATRHI FLIRHSQYHV DGSLEKDRTL TPLGREQAEL TGLRLASLGL KFNKIV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%. Binds to an epitope located within the peptide sequence NWDRREPLSLINVRK as determined by overlapping synthetic peptides.

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt].

Specifications

• Antigen: PGAM5
• Classification: Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96HS1
• Gene Symbols: PGAM5
• Immunogen: Recombinant protein corresponding to Human PGAM5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL0624
• Conjugate: Unconjugated
• Gene: PGAM5
• Gene Alias: 2610528A17Rik; Bcl-XL-binding protein v68; BXLBV68; PGAM family member 5, mitochondrial serine/threonine protein phosphatase; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; PGAM5; Phosphoglycerate mutase family member 5; RGD1312028; serine/threonine-protein phosphatase PGAM5, mitochondrial
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 192111
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid