Invitrogen™ PGAM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540106

Catalog No. PA540106

Description

Recommended positive controls: 293T and HepG2 cells. Predicted reactivity: Mouse (94%), Rat (92%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt].

Specifications

• Antigen: PGAM5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PGAM5
• Gene Alias: 2610528A17Rik; Bcl-XL-binding protein v68; BXLBV68; PGAM family member 5, mitochondrial serine/threonine protein phosphatase; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; PGAM5; Phosphoglycerate mutase family member 5; RGD1312028; serine/threonine-protein phosphatase PGAM5, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 192111
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.62 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol, 0.1M glycine and 0.01% Thimerosal; pH 7
• Gene Accession No.: Q96HS1
• Gene Symbols: PGAM5
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PGAM5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG