Invitrogen™ PGAM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115745

Catalog No. PIPA5115745

Description

Antibody detects endogenous levels of total PGAM5.

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt].

Specifications

• Antigen: PGAM5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PGAM5
• Gene Alias: 2610528A17Rik; Bcl-XL-binding protein v68; BXLBV68; PGAM family member 5, mitochondrial serine/threonine protein phosphatase; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; PGAM5; Phosphoglycerate mutase family member 5; RGD1312028; serine/threonine-protein phosphatase PGAM5, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 192111, 288731, 72542
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q562B5, Q8BX10, Q96HS1
• Gene Symbols: PGAM5
• Immunogen: A synthesized peptide derived from human PGAM5(Accession Q96HS1), corresponding to amino acid residues T156-A206.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov