PGC-1 IHC, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00029

Catalog No. 50-157-1357

Description

The recommended shelf life for this product is 1 year from date of receipt.

PGC1 alpha is a transcriptional coactivator that regulates the genes involved in energy metabolism. It interacts with PPARgamma, which permits it′s interaction with multiple transcription factors. PGC-1 Alpha can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. It may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Specifications

• Antigen: PGC-1
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q9UBK2
• Gene Symbols: PPARGC1A
• Immunogen: Between 250 and 300
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Gene: PPARGC1A
• Gene Alias: LEM6, Ligand effect modulator 6, L-PGC-1alpha, peroxisome proliferative activated receptor, gamma, coactivator 1, PGC1, PGC1A, PGC-1alpha, PGC-1-alpha, PGC-1v, PPAR gamma coactivator variant form, PPARgamma coactivator 1alpha, PPARGC1, PPARGC-1-alpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10891
• Content And Storage: 4° C
• Form: Liquid