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PGC-1 IHC, Polyclonal, Bethyl Laboratories

Catalog No. 501571358
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50-157-1358 10 μL
50-157-1357 100 μL
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Catalog No. 50-157-1358 Supplier Bethyl Laboratories, Inc Supplier No. IHC00029T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

PGC1 alpha is a transcriptional coactivator that regulates the genes involved in energy metabolism. It interacts with PPARgamma, which permits it′s interaction with multiple transcription factors. PGC-1 Alpha can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. It may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Specifications

Antigen PGC-1
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PPARGC1A
Gene Accession No. Q9UBK2
Gene Alias LEM6, Ligand effect modulator 6, L-PGC-1alpha, peroxisome proliferative activated receptor, gamma, coactivator 1, PGC1, PGC1A, PGC-1alpha, PGC-1-alpha, PGC-1v, PPAR gamma coactivator variant form, PPARgamma coactivator 1alpha, PPARGC1, PPARGC-1-alpha
Gene Symbols PPARGC1A
Host Species Rabbit
Immunogen Between 250 and 300
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10891
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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