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Invitrogen™ PGC Monoclonal Antibody (90/11)
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Catalog No. PIMA183392
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200 μg
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PIMA183392 200 μg
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Catalog No. PIMA183392 Supplier Invitrogen™ Supplier No. MA183392
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Description

Mouse Monoclonal Antibody

Mouse anti Human pepsinogen II antibody, clone 90/10 is specific for human pepsinogen II. Less than 1% reactivity has been observed with human pepsinogen I (isozymogens 2-5), porcine pepsinogen, gastrin I, somatostatin, peptide YY and bombesin.

Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGC
Applications ELISA
Classification Monoclonal
Clone 90/11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Citric acid, PBS with <0.1% sodium azide
Gene Pgc
Gene Accession No. P20142
Gene Alias 2210410L06Rik; Gastricsin; pep carboxylase; PEPC; pepcase; pepsin C; pepsinogen C; pepsinogen group II; PG1; Pg-1; Pgc; PGII; preprogastricsin; progastricsin; progastricsin (pepsinogen C); Upg1; Upg-1; Urinary pepsinogen 1
Gene Symbols Pgc
Host Species Mouse
Immunogen Human pepsinogen II.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5225
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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