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Invitrogen™ PGC Polyclonal Antibody
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Catalog No. PIPA596208
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100 μL
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PIPA596208 100 μL
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Catalog No. PIPA596208 Supplier Invitrogen™ Supplier No. PA596208
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver, Mouse heart, Rat liver Immunogen sequence: YFGEISIGTP PQNFLVLFDT GSSNLWVPSV YCQSQACTSH SRFNPSESST YSTNGQTFSL QYGSGSLTGF FGYDTLTVQS IQVPNQEFGL SENEPGTNFV.

Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGC
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.69 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Pgc
Gene Accession No. P04073, P20142, Q9D7R7
Gene Alias 2210410L06Rik; Gastricsin; pep carboxylase; PEPC; pepcase; pepsin C; pepsinogen C; pepsinogen group II; PG1; Pg-1; Pgc; PGII; preprogastricsin; progastricsin; progastricsin (pepsinogen C); Upg1; Upg-1; Urinary pepsinogen 1
Gene Symbols Pgc
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 73-172 of human Pepsinogen II (PG II) (NP_0011598961).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109820, 24864, 5225
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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