Invitrogen™ PGC1 alpha/beta Recombinant Rabbit Monoclonal Antibody (JF09-71)

Catalog No.	Quantity
PIMA532563	100 μL

Catalog No. PIMA532563 Supplier Invitrogen™ Supplier No. MA532563

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.

Specifications

• Antigen: PGC1 alpha/beta
• Applications: Western Blot
• Classification: Recombinant Monoclonal
• Clone: JF09-71
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene: Ppargc1a
• Gene Accession No.: O70343, Q811R2, Q86YN6, Q8VHJ7, Q9QYK2, Q9UBK2
• Gene Alias: 4631412G21Rik; A830037N07Rik; ENSMUSG00000079510; ERR ligand 1; Errl1; Gm11133; LEM6; Ligand effect modulator 6; ligand effect modulator-6; L-PGC-1alpha; PERC; peroxisome proliferative activated receptor gamma coactivator 1; peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma coactivator-1 alpha; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; Pgc1; PGC-1; pgc-1 alpha; pgc-1 beta; PGC-1(alpha); PGC-1(beta); PGC1A; PGC-1alpha; PGC-1-alpha; Pgc-1alphaa; PGC1B; PGC1beta; PGC-1beta; PGC-1-beta; PGC-1beta/ERRL1; PGC-1-related estrogen receptor alpha coactivator; PGC-1v; Pgco1; PPAR gamma coactivator variant form; PPAR Gamma Coactivator-1; PPAR gamma coactivator-1beta protein; PPARG coactivator 1 alpha; PPARG coactivator 1 beta; PPARgamma coactivator 1 beta; PPARgamma coactivator 1alpha; PPAR-gamma coactivator 1-alpha; PPAR-gamma coactivator 1-beta; Ppargc1; Ppargc1a; PPARGC-1-alpha; Ppargc1b; PPARGC-1-beta
• Gene Symbols: Ppargc1a, Ppargc1b
• Host Species: Rabbit
• Immunogen: Synthetic peptide within human pgc1 alpha aa 755-798 and aa 269-323.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10891, 133522, 170826, 19017, 291567, 83516
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG