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PGC1 alpha Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987812
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100 μL
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50-198-7812 100 μL
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Catalog No. 50-198-7812 Supplier Bioss Supplier No. BS7535R
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Description

Rabbit Polyclonal Antibody

PGC1 alpha is a transcriptional coactivator that regulates the genes involved in energy metabolism. It interacts with PPARgamma, which permits it′s interaction with multiple transcription factors. PGC-1 Alpha can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. It may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Specifications

Antigen PGC1 alpha
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Ppargc1a
Gene Accession No. Q9UBK2
Gene Alias A830037N07Rik; ENSMUSG00000079510; Gm11133; I79_015506; LEM6; Ligand effect modulator 6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferative activated receptor gamma coactivator 1; peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; peroxisome proliferator-activated receptor gamma coactivator-1 alpha; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; PGC1; PGC-1; PGC-1(alpha); Pgc1a; Pgc-1alpha; PGC-1-alpha; Pgc-1alphaa; PGC-1v; Pgco1; PPAR gamma coactivator variant form; PPAR Gamma Coactivator-1; PPARG coactivator 1 alpha; PPARgamma coactivator 1alpha; PPAR-gamma coactivator 1-alpha; Ppargc1; Ppargc1a; PPARGC-1-alpha
Gene Symbols Ppargc1a
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PGC1 alpha.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10891
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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