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Invitrogen™ PGCF Polyclonal Antibody
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Catalog No. PIPA589697
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100 μL
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PIPA589697 100 μL
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Catalog No. PIPA589697 Supplier Invitrogen™ Supplier No. PA589697
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HSALIGGETQ MHLLECAHDL KMTDGTYVFV PYDALLYSLP YKHTPYRVLR NNPKLREAYD AVLTITVESQ EKTFYQAFTE AAARGEIPEK LEFDQVSPLF GTIYNSIYFI AQAMNNAMKE NGQAGAASLV QHSRNMQFHG FNQLMRTDSN GNGISEYVIL DTNLKEWELH STYTVDMEME LLRFGGTPIH FPGGRPPRAD AKCWFAEGKI C; Positive Samples: Mouse eye; Cellular Location: Membrane, Single-pass type I membrane protein.

GUCY2F (Guanylate cyclase 2F, retinal) is also named as GUC2F, RETGC2 and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. GUCY2F may play a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. By in situ hybridization, mRNA encoding GUCY2F is found only in the outer nuclear layer and inner segments of photoreceptor cells. By using synthetic peptide antiserum specific for each RetGC subtype, RetGC-2(GUCY2F) can be distinguished from RetGC-1 as a slightly smaller protein in immunoblots of bovine rod outer segments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGCF
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene GUCY2F
Gene Accession No. P51842, Q5SDA5
Gene Alias A930002I06; CYGF; GC2; GC-F; guanylate cyclase 2D-like, membrane (retina-specific); guanylate cyclase 2f; Guanylate cyclase 2F, retinal; guanylate cyclase F; GUC2DL; GUC2F; Gucy2f; RETGC2; RETGC-2; Retinal guanylyl cyclase 2; rod outer segment membrane guanylate cyclase 2; ROS-GC2
Gene Symbols GUCY2F
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_0015132).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116556, 245650
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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