Invitrogen™ PGCF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589697

Catalog No. PIPA589697

Description

Immunogen sequence: HSALIGGETQ MHLLECAHDL KMTDGTYVFV PYDALLYSLP YKHTPYRVLR NNPKLREAYD AVLTITVESQ EKTFYQAFTE AAARGEIPEK LEFDQVSPLF GTIYNSIYFI AQAMNNAMKE NGQAGAASLV QHSRNMQFHG FNQLMRTDSN GNGISEYVIL DTNLKEWELH STYTVDMEME LLRFGGTPIH FPGGRPPRAD AKCWFAEGKI C; Positive Samples: Mouse eye; Cellular Location: Membrane, Single-pass type I membrane protein.

GUCY2F (Guanylate cyclase 2F, retinal) is also named as GUC2F, RETGC2 and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. GUCY2F may play a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. By in situ hybridization, mRNA encoding GUCY2F is found only in the outer nuclear layer and inner segments of photoreceptor cells. By using synthetic peptide antiserum specific for each RetGC subtype, RetGC-2(GUCY2F) can be distinguished from RetGC-1 as a slightly smaller protein in immunoblots of bovine rod outer segments.

Specifications

• Antigen: PGCF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GUCY2F
• Gene Alias: A930002I06; CYGF; GC2; GC-F; guanylate cyclase 2D-like, membrane (retina-specific); guanylate cyclase 2f; Guanylate cyclase 2F, retinal; guanylate cyclase F; GUC2DL; GUC2F; Gucy2f; RETGC2; RETGC-2; Retinal guanylyl cyclase 2; rod outer segment membrane guanylate cyclase 2; ROS-GC2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116556, 245650
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P51842, Q5SDA5
• Gene Symbols: GUCY2F
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_0015132).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG