Invitrogen™ PGK1/PGK2 Recombinant Rabbit Monoclonal Antibody (HL1775)

Catalog No.	Quantity
PIMA547177	100 μL

Catalog No. PIMA547177 Supplier Invitrogen™ Supplier No. MA547177

Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate The encoded protein may also act as a cofactor for polymerase alpha Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Specifications

• Antigen: PGK1/PGK2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: HL1775
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene Accession No.: P29452, P29466, P43527, P48729, P97633, Q8BK63, Q8N752
• Gene Alias: HEL-S-68p; MIG10; PGKA; phosphoglycerate kinase 1
• Host Species: Rabbit
• Immunogen: Recombinant protein of human PGK1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 0, 113927, 122011, 12362, 1452, 834
• Target Species: Human, Mouse, Rat, Zebrafish
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG