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Invitrogen™ PGRMC1 Polyclonal Antibody
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Catalog No. PIPA5120929
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100 μL
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PIPA5120929 100 μL
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Catalog No. PIPA5120929 Supplier Invitrogen™ Supplier No. PA5120929
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, 293T, SW480, OVCAR3, NCI-H460, Mouse liver, Mouse brain. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein. Immunogen sequence: KIVRGDQPAA SGDSDDDEPP PLPRLKRRDF TPAELRRFDG VQDPRILMAI NGKVFDVTKG RKFYGPEGPY GVFAGRDASR GLATFCLDKE ALKDEYDDLS DLTAAQQETL SDWESQFTFK YHHVGKLLKE GEEPTVYSDE EEPKDESARK ND.

The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGRMC1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PGRMC1
Gene Accession No. O00264, O55022, P70580
Gene Alias 25dx; 25-Dx; AA415812; Acidic 25 kDa protein; Dap1; HGNC:16090; HPR6.6; IZA; Lewi; membrane steroid binding protein; membrane-associated progesterone receptor component 1; membrane-bound progesterone receptor; MPR; Pgrmc; Pgrmc1; PPMR; progesterone binding protein; progesterone receptor membrane component 1; steroid membrane binding protein; VEMA; Ventral midline antigen
Gene Symbols PGRMC1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 44-195 of human PGRMC1 (NP_006658.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10857, 291948, 53328
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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