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PGRMC2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563896
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50-156-3896 10 μL
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Catalog No. 50-156-3896 Supplier Bethyl Laboratories, Inc Supplier No. A302954AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.

Specifications

Antigen PGRMC2
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene PGRMC2
Gene Accession No. O15173
Gene Alias DG6, PMBP
Gene Symbols PGRMC2
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10424
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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