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PGRMC2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302954AT

Encompass_Preferred

Catalog No. 50-156-3896


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.
Specifications

Specifications

PGRMC2
Polyclonal
Unconjugated
PGRMC2
DG6, PMBP
Rabbit
Antigen affinity chromatography
RUO
10424
4° C
Liquid
Immunoprecipitation
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
O15173
PGRMC2
Between 1 and 50
10 μL
Primary
Human
Antibody
IgG
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