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Invitrogen™ PGRP-1a Polyclonal Antibody
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Catalog No. PIPA598055
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100 μg
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PIPA598055 100 μg
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Catalog No. PIPA598055 Supplier Invitrogen™ Supplier No. PA598055
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Description

Rabbit Polyclonal Antibody

PGRP-1a Polyclonal Antibody for Western Blot, ELISA

Primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4). PGRP-1a mRNA is highly expressed in esophagus, tonsils and thymus and to lesser extent in the stomach, rectum, and brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGRP-1a
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.86 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene PGLYRP3
Gene Accession No. Q96LB9
Gene Alias Gm420; MGC149197; Peptidoglycan recognition protein 3; peptidoglycan recognition protein I alpha; peptidoglycan recognition protein I-alpha; Peptidoglycan recognition protein intermediate alpha; PGLYRP3; PGLYRPIalpha; PGRPIA; PGRP-Ialpha; PGRP-I-alpha
Gene Symbols PGLYRP3
Host Species Rabbit
Immunogen Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114771
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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