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Invitrogen™ PGRP-1b Monoclonal Antibody (186C426)
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Catalog No. 01676474
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100 μg
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Catalog No. Quantity
01-676-474 100 μg
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Catalog No. 01-676-474 Supplier Invitrogen™ Supplier No. MA141136
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Description

Mouse Monoclonal Antibody

Suggested positive control: human brain tissue, human brain protein.

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGRP-1b
Applications Western Blot
Classification Monoclonal
Clone 186C426
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA and 0.05% sodium azide
Gene PGLYRP4
Gene Accession No. Q96LB8
Gene Alias Gm1478; Gm413; Peptidoglycan recognition protein 4; peptidoglycan recognition protein I beta; peptidoglycan recognition protein I-beta; Peptidoglycan recognition protein intermediate beta; peptidoglycan recognition protein-I-beta; PGLYRP4; PGLYRPIbeta; PGRPIB; PGRP-Ibeta; PGRP-I-beta; SBBI67
Gene Symbols PGLYRP4
Host Species Mouse
Immunogen KLH-conjugated synthetic peptide corresponding to amino acids 95-110 of human PGRP-1 beta.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 310611, 57115
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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