Invitrogen™ PGRP-1b Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116290

Catalog No. PIPA5116290

Description

PGRP-1b Polyclonal Antibody for Western Blot

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).

Specifications

• Antigen: PGRP-1b
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q96LB8
• Gene Symbols: PGLYRP4
• Immunogen: KLH conjugated synthetic peptide between 242-268 amino acids from the Central region of human PGLYRP4.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PGLYRP4
• Gene Alias: Gm1478; Gm413; Peptidoglycan recognition protein 4; peptidoglycan recognition protein I beta; peptidoglycan recognition protein I-beta; Peptidoglycan recognition protein intermediate beta; peptidoglycan recognition protein-I-beta; PGLYRP4; PGLYRPIbeta; PGRPIB; PGRP-Ibeta; PGRP-I-beta; SBBI67
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 57115
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid