Thermo Scientific™ Phadia™ β 2-Glycoprotein I Antibodies for Antiphospholipid Syndrome

Description

Intended for the in vitro quantitative measurement of antibodies directed to β2-Glycoprotein I in human serum and plasma to aid in the diagnosis of antiphospholipid syndrome (APS) and to evaluate the thrombotic risk in patients with systemic lupus erythematosus (SLE).

If present in the patient's specimen, antibodies to β2-Glycoprotein I bind to their specific antigen. After washing away non-bound antibodies, enzyme-labeled antibodies against human IgG (IgM, IgA) antibodies (EliA IgG, IgM, IgA Conjugate™) are added to form an antibody-conjugate complex. After incubation, non-bound conjugate is washed away and the bound complex is incubated with a Development Solution. After stopping the reaction, the fluorescence in the reaction mixture is measured. To evaluate test results, the response for patient samples is compared directly to the response for calibrators.

• The EliA 2-Glycoprotein I IgG (IgM, IgA) Wells are coated with human β2-Glycoprotein I antigen
• The higher the responseβ value, the more specific IgG (IgM, IgA) is present in the specimen
• All conjugates are isotype-specific -- mixed conjugate is not available

Specifications

• Type: EliA Beta2-Glycoprotein I IgM
• For Use With (Application): In-vitro quantitative measurement of Antibodies directed to beta2-Glycoprotein I in Human Serum and Plasma to aid in the diagnosis of antiphospholipid syndrome
• Quantity: 4 x 12 Tests