Invitrogen™ PHAP I Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530552

Catalog No. PIPA530552

Description

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain. Predicted reactivity: Mouse (90%), Rat (91%), Zebrafish (95%), Xenopus laevis (91%), Dog (96%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PHAP I is implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Specifications

• Antigen: PHAP I
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANP32A
• Gene Alias: Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein pp32; Anp32; ANP32A; C15orf1; cerebellar leucine rich acidic nuclear protein; hepatopoietin Cn; HPPCn; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; MAPM; Mapmodulin; MGC119787; MGC150373; PHAP1; PHAPI; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; pp32; Putative HLA-DR-associated protein I; putative human HLA class II associated protein I; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A; W91701
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11737, 8125
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O35381, P39687
• Gene Symbols: ANP32A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ANP32A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov