Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA543663

Invitrogen™ PHC1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA543663
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA543663 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA543663 Supplier Invitrogen™ Supplier No. PA543663
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Peptide sequence: PLSVRAGHGE RDLGNPNTAP PTPELHGINP VFLSSNPSRW SVEEVYEFIA Sequence homology: Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Pig: 93%; Rabbit: 93%; Rat: 86%.

Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1 or RAE28, is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PHC1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PHC1
Gene Accession No. P78364
Gene Alias AW557034; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); early development regulatory protein 1; Edr; Edr1; hPH1; MCPH11; Mph1; PH1; Phc1; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); polyhomeotic-like protein 1; RAE28; RAE-28
Gene Symbols PHC1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human DKFZp686A1782 (aa 901-950).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1911
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.