Invitrogen™ PHC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538047

Catalog No. PIPA538047

Description

A recommended positive control is NIH-3T3 cell lysate. At least six isoforms of PHC3 are known to exist.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Specifications

• Antigen: PHC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHC3
• Gene Alias: E030046K01Rik; early development regulator 3; early development regulatory protein 3; EDR3; homolog of polyhomeotic 3; hPH3; PH3; Phc3; polyhomeotic 3; polyhomeotic homolog 3; polyhomeotic homolog 3 (Drosophila); polyhomeotic like 3; polyhomeotic-like 3 (Drosophila); polyhomeotic-like protein 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 241915, 310258, 80012
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8CHP6, Q8NDX5
• Gene Symbols: PHC3
• Immunogen: 19 amino acid peptide near the amino terminus of human PHC3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov