PHD2 Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
APPA6525	100 μL

Catalog No. APPA6525 Supplier Thermo Scientific Supplier No. PA116525

Description

Rabbit Polyclonal Antibody

This antibody does not react with mouse samples. Suggested positive control: antigen standard for EGLN1 (transient overexpression lysate), human glioblastoma cells.

SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

• Antigen: PHD2
• Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: Egln1
• Gene Accession No.: P59722, Q9GZT9
• Gene Alias: AI503754; C1orf12; C1ORF12 antibody; ECYT3; egl nine homolog 1; egl nine-like protein 1; egl-9 family hypoxia inducible factor 1; egl-9 family hypoxia-inducible factor 1; EGLN 1 EGLN1; EGLN1; HALAH; HIF PH2; HIF prolyl hydroxylase 2; HIF-P4H 2; Hif-p4h-2; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; Hypoxia-inducible factor prolyl hydroxylase 2; ORF13; P4H2; Phd2; PHD-2; PNAS-118; PNAS-137; Prolyl Hy; Prolyl hydroxylase domain-containing protein 2; SM20; SM-20; zinc finger MYND domain-containing protein 6; ZMYND6
• Gene Symbols: Egln1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a C-terminal portion of human PHD2/HIF Prolyl Hydroxylase 2 (between amino acids 350-426)
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 308913, 54583
• Target Species: Human, Non-human Primate, Rat
• Content And Storage: 4° C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov