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Tocris Bioscience™ Phenyl-glutarimide 4'-piperazine
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Catalog No. 7729100
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77-291-00 100 mg
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Description

Piperazine-functionalized cereblon ligand for PROTAC development

Phenyl-glutarimide 4'-piperazine is a piperazine-functionalized cereblon ligand that can be used for PROTAC™ Degrader development. The compound can be used to develop PG-PROTACs that exhibit improved stability to hydrolysis and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material 3-[4-(1-Piperazinyl)phenyl]-2,6-piperidinedione dihydrochloride
CAS 2902651-89-0
Quantity 100 mg
Target Degrader Building Blocks
Molecular Formula C15H19N3O2.2HCl
Purity 95%
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