Invitrogen™ PHF15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555275

Catalog No. PIPA555275

Description

Immunogen sequence: ASVAADSDVQ VLGPAASPKP LGRLRPPRES KVTRRLPGAR PDAGMGPPSA VAERPKVSLH FDTETDGYFS DGEMSDSDVE AEDGGVQRGP REAGAEEVVR MGVLA Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 78%.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt].

Specifications

• Antigen: PHF15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JADE2
• Gene Alias: 1200017K05Rik; AI480685; E3 ubiquitin-protein ligase Jade-2; jade family PHD finger 2; jade family PHD finger protein 2; JADE2; JADE-2; Kiaa0239; mKIAA0239; PHD finger protein 15; Phf15; protein Jade-2; protein Jade-2; E3 ubiquitin-protein ligase Jade-2; si:ch73-202g8.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23338
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NQC1
• Gene Symbols: JADE2
• Immunogen: Recombinant protein corresponding to Human PHF15. Recombinant protein control fragment (Product #RP-93570).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov