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Invitrogen™ PHF17 Polyclonal Antibody
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Catalog No. FEPA5145034
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100 μL
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FEPA5145034 100 μL
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Catalog No. FEPA5145034 Supplier Invitrogen™ Supplier No. PA5145034
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGLEKTFAEA RLISAQQKNG VVMPDHGKRR DNRFHCDLIK GDLKDKSFKQ SHKPLRSTDV SQRHLDNTRA ATSPGVGQSA PGTRKEIVPK CNGSLIKVNY NQ Antigen sequence identity: Mouse 89%; Rat 89%.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653, PubMed:19187766, PubMed:20129055, PubMed:24065767). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation (PubMed:20129055, PubMed:24065767). May also promote acetylation of nucleosomal histone H4 by KAT5 (PubMed:15502158). Promotes apoptosis (PubMed:16046545). May act as a renal tumor suppressor (PubMed:16046545). Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (PubMed:22654112). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PHF17
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene JADE1
Gene Accession No. Q6IE81
Gene Alias AU041499; D530048A03Rik; gene for apoptosis and differentiation in epithelia; jade family PHD finger 1; jade family PHD finger protein 1; Jade1; Jade1 PHD finger protein; KIAA1807; mKIAA1807; PHD finger protein 17; PHD protein Jade-1; Phf17; Protein Jade-1
Gene Symbols JADE1
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 631-732. Recombinant protein control fragment (Product #RP-109729).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79960
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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