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Invitrogen™ PHF17 Polyclonal Antibody
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Catalog No. PIPA554124
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100 μL
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PIPA554124 100 μL
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Catalog No. PIPA554124 Supplier Invitrogen™ Supplier No. PA554124
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VCKVQEQIFN LYTKLLEQER VSGVPSSCSS SSLENMLLFN SPSVGPDAPK IEDLKWHSAF FRKQMGTSLV HSLKKPHKRD PLQNSPGSEG KTLLKQPDL Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653, PubMed:19187766, PubMed:20129055, PubMed:24065767). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation (PubMed:20129055, PubMed:24065767). May also promote acetylation of nucleosomal histone H4 by KAT5 (PubMed:15502158). Promotes apoptosis (PubMed:16046545). May act as a renal tumor suppressor (PubMed:16046545). Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (PubMed:22654112). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PHF17
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene JADE1
Gene Accession No. Q6IE81, Q6ZPI0
Gene Alias AU041499; D530048A03Rik; gene for apoptosis and differentiation in epithelia; jade family PHD finger 1; jade family PHD finger protein 1; Jade1; Jade1 PHD finger protein; KIAA1807; mKIAA1807; PHD finger protein 17; PHD protein Jade-1; Phf17; Protein Jade-1
Gene Symbols JADE1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PHF17. Recombinant protein control fragment (Product #RP-92088).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269424, 310352, 79960
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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