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Invitrogen™ PHF17 Polyclonal Antibody
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Catalog No. PIPA5106428
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100 μL
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PIPA5106428 100 μL
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Catalog No. PIPA5106428 Supplier Invitrogen™ Supplier No. PA5106428
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PHF17.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653, PubMed:19187766, PubMed:20129055, PubMed:24065767). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation (PubMed:20129055, PubMed:24065767). May also promote acetylation of nucleosomal histone H4 by KAT5 (PubMed:15502158). Promotes apoptosis (PubMed:16046545). May act as a renal tumor suppressor (PubMed:16046545). Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (PubMed:22654112). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PHF17
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene JADE1
Gene Accession No. Q6IE81, Q6ZPI0
Gene Alias AU041499; D530048A03Rik; gene for apoptosis and differentiation in epithelia; jade family PHD finger 1; jade family PHD finger protein 1; Jade1; Jade1 PHD finger protein; KIAA1807; mKIAA1807; PHD finger protein 17; PHD protein Jade-1; Phf17; Protein Jade-1
Gene Symbols JADE1
Host Species Rabbit
Immunogen A synthesized peptide derived from human JADE1(Accession Q6IE81), corresponding to amino acid residues S681-N731.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269424, 310352, 79960
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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