Invitrogen™ PHF6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530853

Catalog No. PIPA530853

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Human (99%), Mouse (95%), Pig (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: PHF6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHF6
• Gene Alias: 2700007B13Rik; 4931428F02Rik; BFLS; BORJ; CENP-31; centromere protein 31; Kiaa1823; mKIAA1823; PHD finger protein 6; PHD-like zinc finger protein; PHF6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100359714, 70998, 84295
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8IWS0, Q9D4J7
• Gene Symbols: PHF6
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PHF6. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG