Invitrogen™ PHF7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557594

Catalog No. PIPA557594

Description

Immunogen sequence: KTVKEKKECQ RLRKSAKTRR VTQRKPSSGP VCWLCLREPG DPEKLGEFLQ KDNISVHYFC LILSSKLPQR GQSNRGFHGF LPEDIKKEAA RASRKICFVC Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.

Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.

Specifications

• Antigen: PHF7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHF7
• Gene Alias: 1700006H01Rik; 1700010P14Rik; AI427892; AW555949; HSPC045; HSPC226; NYD-SP6; PHD finger protein 7; PHF7; testicular secretory protein Li 34; testis development protein NYD-SP6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51533
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BWX1
• Gene Symbols: PHF7
• Immunogen: Recombinant protein corresponding to Human PHF7. Recombinant protein control fragment (Product #RP-96248).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov