Invitrogen™ PHGDH Monoclonal Antibody (CL0555)

Catalog No.	Quantity
PIMA531357	100 μL

Catalog No. PIMA531357 Supplier Invitrogen™ Supplier No. MA531357

Description

Mouse Monoclonal Antibody

Immunogen sequence: LEEIWPLCDF ITVHTPLLPS TTGLLNDNTF AQCKKGVRVV NCARGGIVDE GALLRALQSG QCAGAALDVF TEEPPRDRAL VDHENVISCP HLGASTKEAQ SRCGEEIAVQ FVDM Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

PHGDH gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Specifications

• Antigen: PHGDH
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: CL0555
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: PHGDH
• Gene Accession No.: O43175
• Gene Alias: 2-oxoglutarate reductase; 3PGDH; 3-PGDH; 3-phosphoglycerate dehydrogenase; 3-phosphoglycerate dehyrogenase; 4930479N23; A10; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; HEL-S-113; Malate dehydrogenase; NLS; NLS1; PDG; PGAD; PGD; PGDH; PGDH3; Phgdh; PHGDHD; phosphoglycerate dehydrogenase; SERA
• Gene Symbols: PHGDH
• Host Species: Mouse
• Immunogen: Recombinant protein fragment of Human PHGDH (Product #RP-91732)
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26227
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1