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PHLDA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 182631AP150UL
Description
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation.Specifications
PHLDA1 | |
Polyclonal | |
Unconjugated | |
PHLDA1 | |
DT1P1B11, PHLDA1, PHRIP, PQ rich protein, PQR protein, TDAG51 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21664, 22822, 29380 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Western Blot | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q62392, Q8WV24, Q9QZA1 | |
Phlda1 | |
PHLDA1 Fusion Protein Ag13125 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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