PHLPPL Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300661A

Catalog No. 50-155-8150

Description

The recommended shelf life for this product is 1 year from date of receipt.

PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of ′Ser-473′ of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ′Ser-473′ of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.

Specifications

• Antigen: PHLPPL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHLPP2
• Gene Alias: PH domain leucine-rich repeat protein phosphatase-like; PHLPP-like; PHLPP2; PHLPPL; KIAA0931
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23035, 244650
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/ml
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q6ZVD8, Q8BXA7
• Gene Symbols: Phlpp2
• Immunogen: Between 1275 and C-term
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG