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Phorbol 12-myristate 13-acetate, MP Biomedicals™

Catalog No. MP218388201 Shop All MP Biomedicals, Inc Products
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Description

Used to increase the biosynthesis of Heme and the repair and creation of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways

  • PMA (Phorbol 12-myristate 13-acetate) activates protein kinase C (PKC) and is a known TPA (tumor promoting agent)
  • PMA has shown chromosome-breaking (clastogenic) activity
  • Phorbol 12-myristate 13-acetate (PMA) has been shown to induce the activity of PLD1 (phospholipase D1)
  • PMA is a tumor promoter, as seen with protein kinase C (PKC) signaling pathway associated with: gene transcription, cell growth, cell differentiation, programmed cell death, immune pathway, receptor desensitization
  • Phorbol 12-myristate 13-acetate is used to study: growth factors, hormones, cytokines-mediated regulation of cellular growth and differentiation
TRUSTED_SUSTAINABILITY

Specifications

Quantity 1 mg
Melting Point 50°C to 70°C
Color White
Purity ≥98%
Molecular Weight (g/mol) 616.8

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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