Invitrogen™ Phosphatidylinositol 4,5-biphosphate Monoclonal Antibody

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA126438

Catalog No. PIMA126438

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Phosphatidylinositol 4,5-bisphosphate or PIP2 is an important second messenger for a number of signaling processes. When certain extracellular signals are received, Phosphilipase C cleaves phosphatidylinositol into DAG and PIP2. PIP2 has been shown to interact with actin structural proteins including profiling, gelsolin, and cofilin, and demonstrates regulatory function of actin polymerization. It has also been shown to regulate vesicular transport by interacting with proteins like ADP-ribosylation factor and phospholipase D. PIP2 has also been shown to significantly affect intracellular calcium concentrations, which also regulate a variety of activities.

Specifications

• Antigen: Phosphatidylinositol 4,5-biphosphate
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Alias: C45H85O19P3; PIP2
• Immunogen: Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Target Molecule: Chemical

• Applications: ELISA, Radioimmune Assays (RIA)
• Concentration: 1 mg/mL
• Formulation: PBS with 10% BSA and 0.05% sodium azide
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG2b