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Invitrogen™ Phospho-4EBP1 (Ser65) Monoclonal Antibody (T.730.9)
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Catalog No. PIMA514948
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100 μL
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PIMA514948 100 μL
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Catalog No. PIMA514948 Supplier Invitrogen™ Supplier No. MA514948
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-4EBP1 (Ser65)
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone T.730.9
Concentration 156.5 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene EIF4EBP1
Gene Accession No. Q13541, Q60876
Gene Alias 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer65 of mouse 4E-BP1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13685, 1978
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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