Invitrogen™ Phospho-53BP1 (Thr543) Polyclonal Antibody

Catalog No.	Quantity
PIPA517000	100 μL

Catalog No. PIPA517000 Supplier Invitrogen™ Supplier No. PA517000

Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

• Antigen: Phospho-53BP1 (Thr543)
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: TP53BP1
• Gene Accession No.: Q12888
• Gene Alias: 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
• Gene Symbols: TP53BP1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surounding pThr543 of human 53BP1.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7158
• Target Species: Human, Monkey
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG