Invitrogen™ Phospho-53BP2 (Ser698) Polyclonal Antibody

Catalog No.	Quantity
PIPA5105070	100 μL

Catalog No. PIPA5105070

Supplier: Invitrogen™ PA5105070

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ASPP2 only when phosphorylated at Ser698.

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specifications

• Antigen: Phospho-53BP2 (Ser698)
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: TP53BP2
• Gene Accession No.: Q13625
• Gene Alias: 53BP2; Apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; ASPP2; BBP; Bcl2-binding protein; P PPP1R13A; P53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; TP53BP2; transformation related protein 53 binding protein 2; Trp53bp2; tumor protein p53 binding protein 2; tumor protein p53 binding protein, 2; tumor suppressor p53-binding protein 2
• Gene Symbols: TP53BP2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human TP53BP2(Accession Q13625), corresponding to amino acid residues around phosphorylated Ser698.
• Purification Method: Sequential Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 305025, 7159
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov