Phospho-AANAT (Thr29) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1373	100 μL

Catalog No. 50-198-1373 Supplier Bioss Supplier No. BS11448R

Description

Rabbit Polyclonal Antibody

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina. Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Specifications

• Antigen: Phospho-AANAT (Thr29)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Aanat
• Gene Accession No.: Q16613
• Gene Alias: Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; Serotonin acetylase; Serotonin N-acetyltransferase; SNAT
• Gene Symbols: Aanat
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse AANAT around the phosphorylation site of Thr29.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 15
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG